Web生物谷-生物医药大词典 在线翻译. 说明: 将内容放到框中,然后再选择中文到英文,还是英文到中文,点击即可. 中文 → 英文 英文 → 中文. 中文 → 英文 英文 → 中文. 帮助. 1. 可以从各类语言输入到中文,英文两种最常用语言,下一步会增加其它语种。. A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which modify lipids, carbohydrates, or other molecules. Phosphorylation usually results in a functional change of the target protein … See more The chemical activity of a protein kinase involves removing a phosphate group from ATP and covalently attaching it to one of three amino acids that have a free hydroxyl group. Most kinases act on both serine and threonine, … See more Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins that share a conserved catalytic core. The … See more Tyrosine-specific protein kinases (EC 2.7.10.1 and EC 2.7.10.2) phosphorylate tyrosine amino acid residues, and like serine/threonine … See more Histidine kinases are structurally distinct from most other protein kinases and are found mostly in prokaryotes as part of two-component signal … See more Serine/threonine protein kinases (EC 2.7.11.1) phosphorylate the OH group of serine or threonine (which have similar side chains). Activity of these protein kinases can be regulated by specific events (e.g., DNA damage), as well as numerous chemical signals, … See more Some kinases have dual-specificity kinase activities. For example, MEK (MAPKK), which is involved in the MAP kinase cascade, is a both … See more Deregulated kinase activity is a frequent cause of disease, in particular cancer, wherein kinases regulate many aspects that control cell … See more
Elevated basal AMP-activated protein kinase activity sensitizes ...
http://www.informatics.jax.org/vocab/gene_ontology/GO:0004672 WebAug 30, 2024 · 蛋白激酶(protein kinases,简称PK),它是催化蛋白质磷酸化过程的酶。. 多种信号转导途径中都会涉及到一个重要环节-蛋白磷酸化,细胞内大部分重要的生命过 … chinook db download
Enzyme Activity Assays for Protein Kinases: Strategies to ... - PubMed
WebApr 19, 2024 · Protein Kinase C (PKC) is a perfect example of regulation of protein kinase by toxicant gradient. A toxicant acts as a kinase inhibitor. Based on the concentration of … Webgsk2606414是一种选择性的perk抑制剂,ic50值为0.4 nm[1]。 prkr样内质网激酶或蛋白激酶r(pkr)样内质网激酶(perk),也被称为真核翻译起始因子2-α激酶3(eif2ak3),属于i型膜蛋白家族。perk位于内质网(er)中,被错误折叠蛋白引起的er应激所诱导。perk通过磷酸化真核翻译起始因子2(eif2)的α亚基,从而 ... chinook database sql server