WebNov 19, 2010 · Combining adoptive transfer of ex vivo expanded NK cells with IL-15 administration (rhesus recombinant IL-15 10 ug/kg s.c. × 5 days) resulted in only a minimal and transient 24 hour increase in the number of detectable CFSE labeled NK cells in the circulation and bone marrow. WebJan 13, 2011 · We have investigated combining adoptive immunotherapy with cytokine-induced killer (CIK) cells and anti-CD20 monoclonal antibodies (mAb) GA101 or rituximab to optimize B-cell non-Hodgkin lymphoma (B-NHL) therapy.
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WebJan 25, 2024 · The approaches of combining adoptive cell transfer with IC inhibition discussed in this review are summarized in Fig. 3. For a better presentation, we organized these strategies into the following sections: … WebOct 15, 2015 · Current research focusses on defining factors that promote in vivo persistence of transferred cells and ameliorate the immunosuppressive microenvironment. To this end, investigators are evaluating the effects of combining adoptive transfer of antigen-specific T cells with other immunotherapy moieties such as checkpoint inhibitors. happy sleep habits happy child
Antigen-specific T cell therapies for cancer - PubMed
WebJan 16, 2024 · Combining Adoptive Cell Therapy with Cytomegalovirus-Based Vaccine Is Protective against Solid Skin Tumors Front Immunol. 2024 Jan 16;8:1993. doi: 10.3389/fimmu.2024.01993. eCollection 2024. Authors Jeremy M Grenier 1 , Stephen T Yeung 1 , Zhijuan Qiu 2 , Evan R Jellison 1 , Kamal M Khanna 1 Affiliations WebJan 16, 2024 · Adoptive cell therapy in humans and in animal models have been shown to be effective for tumor regression. Thus, in this study, we assessed whether CMV-based vaccines in combination with adoptively … WebMay 29, 2024 · These persistent NK cells were able to mediate ADCC responses without cytokine reactivation in vitro suggesting that combining adoptive NK cell transfer with monoclonal antibody administration deserves evaluation. Ishikawa et al. explored NK cell transfer in combination with trastuzumab or cetuximab in advanced gastric or colorectal … chambers county alabama probate