Cisplatin review
WebMost voted positive review. 39 People found this comment helpful . Stage three cancer at base of tongue. Now 45 months in remission. Received 62 radiation and 21 hrs of …
Cisplatin review
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WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important. WebAug 1, 2007 · Cisplatin is a major antineoplastic drug used for the treatment of solid tumors. Its chief dose-limiting side effect is nephrotoxicity; 20% of patients receiving high-dose …
WebAug 1, 2007 · Cisplatin is a major antineoplastic drug used for the treatment of solid tumors. Its chief dose-limiting side effect is nephrotoxicity; 20% of patients receiving high-dose cisplatin have severe renal dysfunction. Cisplatin-DNA crosslinks cause cytotoxic lesions in tumors and other dividing cells. WebMay 24, 2006 · Background Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the rare complications associated with its use. Case presentation A 42- year-old woman presented with a 20 year-history of hypokalemic metabolic alkalosis with …
WebApr 5, 2024 · Abstract. Cisplatin is a platinum containing drug first approved as an antineoplastic agent in 1978. It remains an important and effective therapy in many forms of cancer today. Cisplatin mediates its … WebMar 15, 2024 · Cisplatin has not yet been recognized as a potential trigger for recall reactions. Although it was part of several reported multidrug trigger combinations, all review works referred to cisplatin as not suspicious, suggesting the combination partner as the effector. We performed a focused systematic literature review aiming to re-evaluate the ...
WebOct 13, 2024 · In this Review, we provide an overview of the mechanisms that underlie cisplatin-induced AKI and CKD and discuss the therapeutic implications of potential …
WebJun 24, 2011 · Interstrand crosslinks (ICLs) are a type of DNA damage that is induced by various chemotherapeutics, such as cisplatin. This Review discusses how these lesions are repaired through multiple ... crywank love tabWebMar 13, 2024 · Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute kidney injury (AKI) which develop due to renal accumulation and biotransformation of CDDP. crywank liveWebA systematic review was performed to evaluate clinical studies that have examined hydration and supplementation strategies to prevent cisplatin-induced nephrotoxicity. … dynamics nav table relationWebDec 1, 2024 · Methods. In this open-label, randomized, phase III study, newly diagnosed patients with advanced NSCLC were initially randomized (R1, 1:1) to receive first-line treatment with cisplatin 75 mg/m 2 plus docetaxel 75 mg/m 2 (DC75) or 60 mg/m 2 (DC60) for up to 4 cycles. Patients without progression were further randomized (R2, 1:2) to best … dynamics nav text to dateWebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular … dynamics nav table locked by another userWebSep 9, 2014 · Cisplatin is a common and effective cancer drug. It has revolutionized the treatment of advanced germ cell tumors which were previously considered highly fatal.1-3Side effects (including peripheral neuropathy) and acquired resistance unfortunately have limited its use4and paved the way for the development of new compounds. crywank lyricsWebMar 15, 2024 · Cisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head … crywank meaning