Cilastatin molecular weight

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August undefined, 2024

WebSep 4, 2024 · Imipenem / Cilastatin Formulation Version 8.0 Revision Date: 23.08.2024 SDS Number: 15841-00026 Date of last issue: 09.04.2024 Date of first issue: 05.11.2014 7 / 16 Explosive properties : Not explosive Oxidizing properties : The substance or mixture is not classified as oxidizing. Molecular weight : No data available WebHome / Products / Cilastatin EP Impurity A HCl (Mixture Of Diastereomers) Cilastatin EP Impurity A HCl (Mixture Of Diastereomers) Synonym ... Molecular Weight 442.58. Catalogue Number AR-C02759. Parent Drug CILASTATIN. Cannot find what you are looking for? Send us your request to receive a quotation. Main menu. Home.

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WebCilastatin ammonium salt United States Pharmacopeia (USP) Reference Standard Empirical Formula (Hill Notation): C16H26N2O5S · NH3 CAS Number: 877674-82-3 … WebCilastatin is excreted primarily in unchanged form in the urine, but about 12% of the drug appears as the metabolite N-acetylcilastatin [ 485 ]. In neonatal studies, the intravenous … curly goldendoodle for adoption

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Weboff-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water, and slightly soluble in methanol. Its empirical formula is C 12H 17N 3O 4S•H 2O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. Its chemical name is [R-[R*, S*-(Z)]]-7- WebCilastatin UNII 141A6AMN38 Molecular formula C 16 H 26 N 2 O 5 S Molecular weight 358.45 Percent composition C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% … WebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, … curly goose

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WebCilastatin(MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Quality confirmed by NMR & HPLC. See customer reviews, validations & product … Webnonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12H 17N 3O … curly goldendoodle puppiesWebIt is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. curly goose seeven hill sa

"WebCilastatin Molecular Formula CHNOS Average mass 358.453 Da Monoisotopic mass 358.156250 Da ChemSpider ID 4940183 - Double-bond stereo - 2 of 2 defined stereocentres More details: Featured data source … " - Cilastatin molecular weight

Cilastatin molecular weight

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WebName: Cilastatin CAS#: 82009-34-5 (free acid) Chemical Formula: C16H26N2O5S Exact Mass: 358.15624 Molecular Weight: 358.45 Elemental Analysis: C, 53.61; H, 7.31; N, 7.82; O, 22.32; S, 8.95 Price and Availability Technical data Biological activity Solubility and formulation Protocols Calculators References Webwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C. 12. H. 17. N. 3. O. 4. S•H. 2. O, and its structural . formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. Its chemical name is sodium (Z ...

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WebMolecular Formula: C 16 H 25 N 2 O 5 S. Na. Molecular Weight: 357.45 22.99. Download SDS. Download COA. Related Product. C-136001. ... C-136002. Cilastatin EP Impurity C. C 22 H 36 N 2 O 6 S. M.W. 456.61. C-136003. Cilastatin. CAS No. 82009-34-5. C 16 H 26 N 2 O 3 S. M.W. 358.45. C-136004. Cilastatin EP Impurity A HCl (Mixture of … Webcilastatin sodium " within Products. Sort by Relevance. All Photos (1) Cilastatin sodium. Synonym(s): Cilastatin sodium salt. Empirical Formula (Hill Notation): C 16 H 25 N 2 NaO 5 S. ... Molecular Weight: 358.45. Compare Product No. Description SDS Pricing; SML1283: 50 mg/mL in DMSO/H 2 O, 1:1: Expand. Hide. Match Criteria: Product Name ...

WebFigure 1: Imipenem molecular structure (molecular weight = 299.347 grams/mole). Figure 2: Cilastatin molecular structure (molecular weight = 358.454 grams/mole). Meropenem Meropenem is a derivative of thienamycin. It does not require co-administration with cilastatin because it is not sensitive to renal dipeptidase. WebCombination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. ... Molecular Formula. C12-H17-N3-O4-S.C16-H26-N2-O5-S. Molecular Weight. 657.8057 ...

WebApr 15, 2024 · Her treatment with unspecified low molecular weight heparin was discontinued and she started receiving treatment with acenocoumarol. Within the third … WebOct 6, 2024 · It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of 380.43. It is very soluble in water and in methanol. Its empirical formula is C 16 H 25 N 2 O 5 SNa, and its structural formula is: Imipenem and Cilastatin for Injection, USP (I.V.) is buffered to provide solutions in the pH range of 6.5 to 8.5.

WebAdditional Names: Cilastatin sodium Molecular Formula: C16H25N2NaO5S Molecular Weight: 380.43 Percent Composition: C 50.51%, H 6.62%, N 7.36%, Na 6.04%, O 21.03%, S 8.43% Properties: Off-white to yellowish-white hygroscopic, amorphous solid. pKa1 2.0; pKa2 4.4; pKa3 9.2. Very sol in water, methanol. pKa: pKa1 2.0; pKa2 4.4; pKa3 9.2

WebThe mean serum half-life of imipenem is about 2 hours, whereas that of cilastatin is 5 to 6.4 hours [488]. The half-life for both drugs is inversely related to birth weight and … curly goosebumpsWebCilastatin sodium salt (≥ 98% HPLC); Cilastatin sodium salt is off-white to yellowish-white, hygroscopic, amorphous compound; Inhibitor of dehydropeptidase I; Inhibitor of the renal … curly gostomskiWebFeb 15, 2016 · Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens. Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum … curly goose urban homesteadhttp://editor.fresenius-kabi.us/PIs/US-PH-Imipenem-and-Cilastatin-for-Inj-USP-FK-451205C-05-2015-PI.pdf curly goose sevenhillWebMolecular Formula C13H20ClNO3 Molecular Weight 273.76 Catalogue Number AR-C02770 Parent Drug CILASTATIN CAS Number 877674-77-6 Cilastatin Ammonium Salt Synonym ammonium (Z)-7-(((R)-2-amino-2-carboxyethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoate Molecular Formula C16H25N2O5S . … curly grass fernWeb199 rows · Aug 29, 2007 · The total clearance of imipenem is 0.2 L/h/kg. 8 When used alone, the renal clearance is 0.05 L/h/kg. In combination with cilastatin the renal … curly golden retriever coatsWebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, respectively, approximately 3.2 and 1.9 times the RHD (based on body surface area). ... It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of … curly grass pattern