Bystander effect radiology
WebNational Center for Biotechnology Information WebUpon radiation-exposure the bystander effect is so far mainly identified using in vitro cell cultures. Mothersill and Seymour [2] found that medium from low-LET irradiated cell cultures could reduce the survival of non-irradiated cells. The effect was cell-type dependent and recognized already at low radiation doses with no further effect at ...
Bystander effect radiology
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WebAug 1, 2014 · The bystander effect has numerous associated phenomena, including adaptive response, genomic instability, and abscopal effects. Also, the bystander effect can influence radiation... WebWhen cells are in close contact, allowing gap junction communication, the bystander effect is a much larger magnitude than the phenomenon demonstrated in medium transfer experiments. A bystander effect has been demonstrated for both high- and low-LET radiations but it is usually larger for densely ionizing radiation such as alpha particles.
WebJan 9, 2015 · We assessed the effect of apoptotic bystander cells on a T cell ELISPOT assay by selectively inducing B cell apoptosis using α-CD20 mAbs. The presence of large numbers of apoptotic B cells did not affect T cell functionality. In contrast, when PBMC were stored under unfavorable conditions, leading to damage and apoptosis in the T cells as … WebJun 1, 2024 · Radiation-induced bystander effect (RIBE) and abscopal effect (RIAE) are non-target cellular responses outside the radiation field. It has been recognized that these effects are of great significance to both radiation protection of environmental low-dose radiation and clinical radiotherapy in which the anti-tumor abscopal effect is even …
WebOct 1, 2024 · The effect associated with spatial fractionation is thought to be the result of contributions of bystander/abscopal effects [6] and induced antitumour immune response [7]. ... Development of... WebJun 1, 2011 · The term radiation-induced bystander effect is used to describe radiation-induced biological changes that manifest in unirradiated cells remaining within an irradiated cell population. Despite their failure to fit into the framework of classical radiobiology, radiation-induced bystander effects have entered the mainstream and have become …
WebSpace radiation induced bystander effect in estimating the carcinogenic risk due to galactic cosmic rays
WebMar 16, 2024 · Radiation-induced bystander effects (RIBE) describe the biological events occurring in non-targeted cells in the vicinity of irradiated ones. ... X-rays-Induced Bystander Effect Consists in the Formation of DNA Breaks in a Calcium-Dependent Manner: Influence of the Experimental Procedure and the Individual Factor … clearance newsWebAug 28, 2014 · Radiation-induced bystander effects are defined as biological effects expressed after irradiation by cells whose nuclei have not been directly irradiated. … clearance nicolette bed black horchowWebOct 2, 2016 · In summary, Siva and colleagues have demonstrated the radiation bystander phenomenon manifested as persistent DNA damage foci in the hair follicles well outside … clearance new orleans saints merchandiseThe radiation-induced bystander effect (bystander effect) is the phenomenon in which unirradiated cells exhibit irradiated effects as a result of signals received from nearby irradiated cells. In November 1992, Hatsumi Nagasawa and John B. Little first reported this radiobiological phenomenon. See more There is evidence that targeted cytoplasmic irradiation results in mutation in the nucleus of the hit cells. Cells that are not directly hit by an alpha particle, but are in the vicinity of one that is hit, also contribute to the … See more Note that the bystander effect is not the same as the abscopal effect. The abscopal effect is a phenomenon where the response to … See more The demonstration of a bystander effect in 3D human tissues and, more recently, in whole organisms have clear implication of the potential … See more This effect may also contribute to the final biological consequences of exposure to low doses of radiation. However, there is currently insufficient evidence to suggest that the bystander … See more clearance new carsWebThe radiation-induced bystander effect is defined as the response of cells to the consequences of their neighbors being irradiated and has been well characterized in vitro . There is a close interrelationship between bystander responses and the abscopal responses, which occur in tissues remote from the irradiation field and this is driven by ... clearance nightiesWebThe term bystander effect describes the ability of cells affected by irradiation to convey manifestations of damage to other cells not directly targeted for irradiation. An irradiated cell can send out a signal and induce a response in a … clearance nightstand factoriesWebJun 17, 2024 · Our previous study demonstrated that radiation-induced bystander effects (RIBE) of irradiated recipients decreased the long-term repopulating ability of transplanted mouse HSCs. However, RIBE on transplanted human HSCs have not been studied. clearance niere berechnen